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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 3.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 0.10 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 10.00 µM A2058 Homo sapiens